![]() Now when assessing the association of the occurrence of grey hair with mortality after stroke we might find indeed an association. Confounding occurs- according to Fletcher and Fletcher 1 –if two factors are associated with each other but only one of the two factors is in truth association with the outcome of interest 1.įor example the hypothesis is that “grey hair “ is a risk factor for stroke mortality. This can happen when there is “confounding” at work. However, a factor may seem to be linked with another factor although in truth there is no such independent association. ![]() In clinical stroke investigations, especially in the setting of case control or cohort studies researchers try to find “true” associations of one variable of interest with another variable. ![]() When reading clinical research papers often the words “controlling for confounding” or “adjusting for potential confounders” are used, but what exactly is the meaning of these sentences?
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